First you need to very clearly define your understanding of GTO- Do you mean solver equilibrium play? Which is what most people think is GTO.
Humans are incapable of replicating GTO play, every time you play poker you are playing exploit poker. Why? Because you are never getting the Villains range 100% correct. There is no way for you to know the frequency that a V uses to take their actions.
The moment you know the frequency is when the V is wildly unbalanced and therefore can be exploited. Think NITS and MANIACS
Whenever we play poker what we are doing always is trying to figure out what mistake types our V are making.
Not the exact mistake frequency but the over arching concepts- They are passive- their bet sizes reflect their
hands etc etc
So we use GTO solver charts to set our baseline and adapt based on table dynamics and player pool tendencies.
The famous quote is true "Poker is an easy game to learn but takes a lifetime to master"

