I will echo much of what gord has said, in that PT really starts to show it's teeth when you've built up a large db of hands. A couple of things that I would add to what gord has said:-
1) There is a facility to filter by hand type (eg suited aces, suited connector etc). It's well worth looking at this on a regular basis as I'm sure you will be surprised at hand that you though would be profitable that are not. A big health warning here - don't jump to wrong conclusions on the basis of a few hundred hands. If I took my PT stats for the last 500 hands, they would show pocket A's as being unprofitable - but I'm tempted to continue to raise with them pre-flop rather than throwing them away!
2) If you have a look around on the PT forum (or possibly even within PT help) you will find a link to a tutorial in PDF format. You have to pay a few $'s for it, but it goes into great depth, and is very informative. I'd recommend it. If you can't find the link, post back and I'll have a look around myself.
3) I'd recommend that you convert the db to Postgre rather than using the access db (particularly if you are going to build up a large db - and if you're not, why did you buy it)! Don't worry if you don't know much (or anything) about PL/SQL the conversion is pretty straight forward if you follow the instructions provided.
4) One thing that you can do from day 1 is to review your own performance. I usually dedicate a small amount of time after every session to replay any hand where i lost more than 2 BB's (you can revise this to suit your needs of course). It's much easier to play a hand in retrospect, but you will be surprised how much you learn, and how of en you use it in a similar situation in the future.
I'll not go into detail of how to use the software, because it's pretty intuitive when you get used to it. The PT forums are pretty good if you need help and you can always post back here with specific questions, there are plenty of us that use it.