Don't play cash games with "broken stacks" (lower than 100bb and without auto buy-in): the good REGs will notice that you are recreative or inexperienced quickly and will focus to exploit more your game...
Good players want to have bigger stacks in cash games because they are winners, so they are able to get way more chips from you when they have their best hands
Imagine if you have the nut and you had only 50bb to play against a player with 300bb in a situation that he is facing a really unpredictable cooler... you could double it to 600bb, but your decision to play short stack (with 50bb) would make you double up only to 100bb, which, in this case, is 6x lower than what you would be able to get.
But all I said is for winner players, so if you are not a winner player, but just someone who plays only for fun, you would not want to play with larger stacks, because you would loose way more money than you would in the same amount of time.