Now try combining my comment with eetenor's. If we play 75s and flop say, a flush draw and back door straight, if we are out of position, we either check and hope that Villain doesn't bet or c-bet large, or we blocker bet it, in which case we don't get a great read if he flats (although we do get the next street at our own price).
However, if we are in position, usually Villain will check and WE can c-bet. ; ) If he folds, great, we win with a 7-high. If he calls, then we whiff the turn, and barrel. Repeat the process.
Here, we reach a branch in the tree. We are either going to hit our flush or not.
If we hit the flush, he bets, we flat and almost always win. He checks, we bet value, he probably folds. That's okay because he already paid us on the previous 2 streets.
If the river busts all draws (including ours) and he checks, we barrel, and it's quite likely that he folds, because he was also chasing a draw. ; ) Now sometimes he'll call and we will lose, but even staunch calling stations will fold a river if they chase a draw and bust. This is a common exploitative tactic (especially against players who limp-call with high frequency). This is what Negreanu is talking about when he says, "If we bust on the river we can turn our aggression into a bluff." It is certainly not risk free (no bluff ever is), but it can be an extremely successful tactic, especially with deep stacks that are fully playable and can absorb a 10-20bb bad luck loss.
See, this is a pot that we win WITHOUT HITTING, but it is much easier to do IN POSITION. ; )